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DSIP

Also known as Delta Sleep-Inducing Peptide

Sleep-related peptide with human IV infusion studies showing sleep pressure effects. Mechanism uncertain.

Tier Bmed–high riskintermediate
Tier B
Evidence
Acute / short run
Protocol
med–high
Risk
intrav.
Route

Not Approved

This substance is not approved by any major regulatory body for human therapeutic use. All information is derived from preclinical research, limited clinical studies, or off-label contexts.

Evidence visual

DSIP evidence and risk matrix

intermediate researcher fit

Evidence

Tier B

Risk

med high

Regulatory

not approved

WADA

none

FDA

unknown

Route

intravenous

Higher-confidence evidence profile, but regulatory and sourcing checks still matter.

Overview

DSIP (Delta Sleep-Inducing Peptide) has uncertain biology and receptor targets, but human studies exist. IV infusions at 25 nmol/kg show reported sleep pressure effects. The evidence is older and mixed. Mechanistic certainty is low, and the contested biology increases the need for sourcing credibility.

Decision path

Where DSIP fits in the research path.

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2 related goals
  1. 01

    Read evidence

  2. 02

    Check risk

  3. 03

    Compare options

  4. 04

    Build plan

Peptide research path

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Research Details

Mechanism of Action

Biology and receptor targets remain unclear; human studies exist but mechanistic certainty is low.

Administration Routes

intravenous, subcutaneous

Study Dose Range

Human: slow IV infusion at 25 nmol/kg.

Expected Effects

Sleep pressure effects in some human studies; outcomes inconsistent across trials.

Dosing Timeline

Acute subjective effects reported after dosing; sleep architecture outcomes assessed same day/night.

Contraindications

No established label.

Adverse Effects

Limited modern safety data; moderate uncertainty.

Interaction Notes

Unknown; avoid polypharmacy recommendations.

Cost at a glance

Typical cycle cost

€8.02

Estimated monthly

€16.05

Protocol style

Acute / short run

Intermittent

Estimate confidence

High confidence

Assumes roughly 1.5 mg4 mg per cycle, using 1 tracked affiliated listing.

Best treated as acute or short-run use instead of a classic cycle.

Known Interactions

Caution

Semax

CNS-active peptide combination; limited human safety basis.

Caution

Selank

CNS-active peptide combination; limited human safety basis.

Frequently Compared

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Hexarelin

Tier B-C

Semax

Tier B-C

Selank

Tier B-C

Oxytocin

Tier A

Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.

Sources and review notes

  1. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks - U.S. Food and Drug Administration - accessed 2026-05-15

    Used for FDA compounding-risk context and peptide safety flags.

  2. The Prohibited List - World Anti-Doping Agency - accessed 2026-05-15

    Used for athlete-facing WADA risk and peptide-class restrictions.

  3. Peptide therapeutics: current status and future directions - PubMed / Nature Reviews Drug Discovery - accessed 2026-05-15

    Used for broad peptide-therapeutics background and evidence framing.

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