Hexarelin
Also known as Examorelin
GHRP-class secretagogue with stronger GH stimulation and studied sleep-endocrine effects.
WADA S2
This substance falls under WADA S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics). If you are subject to anti-doping rules, this category of substances is prohibited at all times.
GH Axis
This substance modulates the growth hormone axis. GH-axis stimulation carries risks including glucose intolerance, fluid retention, and theoretical concerns about sustained IGF-1 elevation.
Evidence visual
Hexarelin evidence and risk matrix
advanced researcher fit
Evidence
Tier B-C
Risk
high
Regulatory
not approved
WADA
S2
FDA
unknown
Route
subcutaneous
Mixed evidence profile. Useful for comparison, not a standalone protocol decision.
Overview
Hexarelin (examorelin) is a GHRP-class secretagogue often showing stronger GH stimulation than some peers. Human volunteer studies used repetitive administration (e.g., 4x50 µg across night hours) to evaluate GH/ACTH/cortisol/prolactin and sleep EEG outcomes. Endocrine spillover effects have been studied.
Decision path
Where Hexarelin fits in the research path.
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Peptide research path
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Research Details
GH secretagogue; often stronger GH stimulation vs some peers; spillover endocrine effects studied.
subcutaneous, intravenous
Human: repetitive 4x50 µg across night hours in sleep-endocrine studies.
GH-axis modulation; sleep architecture research interest.
Acute endocrine effects; sleep effects studied overnight.
No formal label.
Endocrine spillover (ACTH, cortisol, prolactin).
Unknown; caution with other GH-axis compounds.
Cost at a glance
No reliable cycle cost estimate yet. We need cleaner listing price and pack-size data before showing a trustworthy number.
Known Interactions
Hexarelin plus MK-677 creates multiple GHS-pathway inputs with limited combination safety support.
Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.
Sources and review notes
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks - U.S. Food and Drug Administration - accessed 2026-05-15
Used for FDA compounding-risk context and peptide safety flags.
- The Prohibited List - World Anti-Doping Agency - accessed 2026-05-15
Used for athlete-facing WADA risk and peptide-class restrictions.
- Peptide therapeutics: current status and future directions - PubMed / Nature Reviews Drug Discovery - accessed 2026-05-15
Used for broad peptide-therapeutics background and evidence framing.
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