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Angiotensin 1-7

Also known as Ang-(1-7) · Mas receptor ligand

Protective renin-angiotensin-system peptide studied for vascular, anti-inflammatory, and anti-fibrotic effects.

Tier Blow riskadvanced
Tier B
Evidence
Protocol
low
Risk
intrav.
Route

Evidence visual

Angiotensin 1-7 evidence and risk matrix

advanced researcher fit

Evidence

Tier B

Risk

low

Regulatory

investigational

WADA

none

FDA

none

Route

intravenous

Higher-confidence evidence profile, but regulatory and sourcing checks still matter.

Overview

Angiotensin 1-7 is a heptapeptide in the protective arm of the renin-angiotensin system. Small human studies and translational work suggest vascular, anti-inflammatory, and anti-fibrotic effects, but it remains investigational and route-specific. It is better understood than many fringe peptides, though still far from consumer-ready.

Decision path

Where Angiotensin 1-7 fits in the research path.

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2 related goals
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  2. 02

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  3. 03

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  4. 04

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Peptide research path

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Research Details

Mechanism of Action

Mas receptor agonist that promotes vasodilation, nitric-oxide signaling, and anti-inflammatory/anti-fibrotic effects.

Administration Routes

intravenous, subcutaneous

Study Dose Range

Human research usually uses IV infusion protocols rather than routine self-administration.

Expected Effects

Potential endothelial, anti-inflammatory, and anti-fibrotic benefits in vascular and pulmonary research settings.

Dosing Timeline

Hemodynamic effects can appear quickly during infusion; structural outcomes are studied over longer periods.

Contraindications

Avoid in hypotension, volume depletion, and use caution with ACE inhibitors or ARBs.

Adverse Effects

Main practical risk is hypotension or reflex tachycardia, especially in combination with other RAAS-active therapies.

Interaction Notes

Likely additive blood-pressure lowering with ACE inhibitors, ARBs, and other vasodilating strategies.

Cost at a glance

No reliable cycle cost estimate yet. We need cleaner listing price and pack-size data before showing a trustworthy number.

Known Interactions

Caution

Vasoactive Intestinal Peptide

Both can shift vascular tone; combined use raises hypotension and perfusion-management uncertainty.

Frequently Compared

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Tier C-D

FOXO4-DRI

Tier C

Information provided for educational and research reference only. Not medical advice. Not for diagnosing, treating, curing, or preventing disease. Products referenced are labeled Research Use Only (RUO) by vendors; not for human or veterinary use.

Sources and review notes

  1. Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks - U.S. Food and Drug Administration - accessed 2026-05-15

    Used for FDA compounding-risk context and peptide safety flags.

  2. The Prohibited List - World Anti-Doping Agency - accessed 2026-05-15

    Used for athlete-facing WADA risk and peptide-class restrictions.

  3. Peptide therapeutics: current status and future directions - PubMed / Nature Reviews Drug Discovery - accessed 2026-05-15

    Used for broad peptide-therapeutics background and evidence framing.

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